منابع مشابه
Transcranial sonothrombolysis using high-intensity focused ultrasound: impact of increasing output power on clot fragmentation
BACKGROUND The primary goal of this study was to investigate the relationship between increasing output power levels and clot fragmentation during high-intensity focused ultrasound (HIFU)-induced thrombolysis. METHODS A HIFU headsystem, designed for brain applications in humans, was used for this project. A human calvarium was mounted inside the water-filled hemispheric transducer. Artificial...
متن کاملNormal findings on pretreatment transcranial ultrasound in patients treated with sonothrombolysis.
In populations with a high (≥14) median National Institute of Health Stroke Score (NIHSS), a normal finding of Thrombolysis in Brain Ischemia grade 5 (TIBI 5) in the artery of interest has been reported to be an unusual finding when transcranial ultrasound is performed during thrombolysis. In such instances, a stroke mimic can be suspected, but there are alternative pathophysiological explanati...
متن کاملSonothrombolysis for acute ischaemic stroke.
BACKGROUND Sonothrombolysis is a promising but unproven tool for treating acute ischaemic stroke. There is an ongoing debate about the efficacy, safety, technical aspects of ultrasound administration and the possible potentiating effect of microbubbles. OBJECTIVES To assess the effectiveness and safety of sonothrombolysis in patients with acute ischaemic stroke. SEARCH METHODS We searched t...
متن کاملSonothrombolysis With Transcranial Color-Coded Sonography and Recombinant Tissue-Type Plasminogen Activator in Acute Middle Cerebral Artery Main Stem Occlusion
Background and Purpose—Sonothrombolysis is a new treatment approach in acute ischemic stroke. The results of a monocenter, randomized clinical study are presented. Methods—Subjects with acute middle cerebral artery main stem occlusion were randomized into a target group receiving 1-hour transcranial continuous insonation using a 1.8-MHz Doppler ultrasound (US) probe or a control group. All unde...
متن کاملInertial cavitation detection during in-vitro sonothrombolysis
Background Being cardiovascular diseases the leading cause of death worldwide, a prompt intervention is needed to restore blood flow. Sonothrombolysis with/without addiction of thrombolytic drugs is explored as a promising solution, thanks to its non-invasiveness, precision and action quickness. Even if the involved mechanisms are not completely understood, acoustic cavitation seems to play a s...
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ژورنال
عنوان ژورنال: Rinsho Shinkeigaku
سال: 2009
ISSN: 0009-918X,1882-0654
DOI: 10.5692/clinicalneurol.49.804